Tough year for science but advances continue U.S. defunding of science has had a particularly damaging effect on climate and health research, but other countries – and the private sector – are pushing ahead with new advances ASTRONOMY James Webb Telescope reveals 29th moon of Uranus – just 10km wide S/2025-U1 Vera Rubin Observatory, Chile promises best views yet of distant galaxies SPACEFLIGHT Annual record 299 orbital launches, including reusable launch vehicles Falcon-9 (left) and New Glenn, robotic moon landers Odysseus – first private moon lander PUBLIC HEALTH Wolbito do Brasil mosquito factory breeds one million insects infected with harmless Wolbachia – blocking ability to spread harmful pathogens e.g. dengue fever ARTIFICIAL INTELLIGENCE Amid an AI boom, Chinese DeepSeek matches other large language models with fraction of hardware and energy GENE THERAPY Huntington’s disease successfully treated Mutant messenger-RNA in cell produces toxic protein Engineered mRNA injected into brain Binds and destroys mutant mRNA METAL ORGANIC FRAMEWORKS Molecular “sponges” revolutionise chemistry Cavity Can harvest water from air, capture CO2, store hydrogen safely U.S. SCIENTIFIC INFLUENCE ON THE WANE? Publications (000s) Collaborative output (000s) U.S. China U.S.-EU collaboration U.S.-China China-EU 250 500 750 1000 2000 2005 2010 2015 2020 25 50 75 100 Sources: Nature, BBC, Nobel Institute Pictures: Vera Rubin Observatory © GRAPHIC NEWS