U.S. agrees deal over opioid sales ------------------------------------------- The Sackler family, owners of Purdue Pharma, have reached a deal to pay up to $6 billion in cash to resolve widespread litigation alleging that they fuelled the U.S. opioid epidemic ------------------------------------------- All opioids Prescription opioids 1996: Purdue Pharma introduces OxyContin. Aggressive marketing boosts annual sales from $48 million to $1.1 billion by 2000 1997: OxyContin prescriptions increase from 670,000 to around 6.2 million by 2002 2001: Purdue pays some 670 sales representatives $40 million in incentive bonuses 2015: Dr. Richard Sackler (above left), former president of Purdue Pharma, denies company has any responsibility for opioid crisis 2020: Deaths from prescription opioids increase by 477% since 1999 Opioid deaths 1999-2020 564,522 Prescription opioid deaths 263,060 70 60 50 40 30 20 10 0 99 00 01 02 03 04 05 06 07 08 09 10 11 12 13 14 15 16 17 18 19 20 8,050 13,756 17,545 20,422 23,166 28,647 33,091 42,249 47,600 49,860 68,630 3,442 8,577 11,589 13,523 14,240 14,838 15,281 17,087 17,029 14,139 16,416 ------------------------------------------- Sources: CDC, Nature, ProPublica, Reuters Picture: ProPublica © GRAPHIC NEWS