How AstraZeneca/Oxford vaccine works 

The Oxford University and AstraZeneca Covid-19 vaccine can prevent up to 90% of people contracting coronavirus when it is administered as a half dose followed by a full dose at least one month apart


Sars-CoV-2

Spike protein: Gene is cut from Sars-CoV-2 genome

Spike protein

Virus genome

Adenovirus: Unable to cause disease

Gene: Inserted into DNA of adenovirus which acts as vector in vaccine

Vaccine: Induces spike protein antigen – triggers antibody immune response

Human immune system: Produces antibodies against spike proteins

If infected: Immune system attacks SARS-Cov-2

Antibodies

Vaccine: Can be stored in refrigerator at 2-8°C. Two doses of vaccine are required


Sources: Reuters, Oxford Vaccine Trial, University of Oxford
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