Cow-free burgers grown in the lab Meat grown from cultured cells – so-called “clean meat” – is made by taking muscle tissue from an animal, collecting stem cells from the sample and multiplying them dramatically into strands of muscle tissue 1 Small biopsy is taken from animal under anaesthesia 2 Myosatellite cells: Stem cells of muscles are separated from sample. Satellite cells are used to produce cell starter culture 3 Cell proliferation: Cells transferred to bioreactor along with growth factors, which cause cells to multiply Bioreactor: Growth medium is warmed to body temperature (37 degrees Celsius), 5% CO2 to mimic blood carbon dioxide levels, plus oxygen, salt, sugars and growth factors 4 Cellular differentiation: Signalling molecules (proteins) added to growth medium make cells differentiate into muscle, fat and connective tissue Muscle cells merge to form myotubes – 0.3mm-long fibres 5 Myotubes spontaneously contract and align to form myofibrils, muscle fibres, fibre bundles, and finally small strands of muscle tissue 6 Around 10,000 strands needed to produce 100 grams of meat which can be processed using standard technologies Myofibrils ------------------------------ Sources: Dr. Liz Specht, Good Food Institute Picture: Mosa Meat © GRAPHIC NEWS