Big pharma megamerger --------------------------------------------------------------------- A $160 billion deal to merge Pfizer and Dublin-based Allergan will create a drug powerhouse with combined revenue of $62.7bn. Pfizer will move its tax base to Ireland to slash its U.S. tax bill by $21bn --------------------------------------------------------------------- Top 10 pharmaceutical companies by 2014 revenue Johnson & Johnson $74.33bn Novartis $57.99bn Roche $49.86bn Pfizer $49.61bn Allergan $13.10bn Sanofi $43.07bn Merck & Co. $42.24bn GlaxoSmithKline $37.96bn AstraZeneca $26.10bn Bayer HealthCare $25.47bn Gilead Sciences $24.474bn 0 10 20 30 40 50 60 70 80 --------------------------------------------------------------------- Top-selling medications Lyrica – $5.16 billion (epilepsy, neuropathy) Prevnar – $4.46 billion (prevention of pneumococcal pneumonia) Viagra – $1.68 billion (erectile dysfunction) Botox – $2 billion* (anti-wrinkle treatment) Restasis – $940 million* (dry-eye treatment) --------------------------------------------------------------------- Sources: Fierce Pharma, Contract Pharma, Statista *2013 figures words 122